TCF12

Across TCGA patient cohorts, TCF12 protein abundance is significantly associated with the RNA expression of many other genes, with 12,356 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TCF12-associated genes across cancer lineages are DCHS1, SCARF2, and RCOR2. Each is linked with TCF12 in more than 4 cancer types. Because this analysis shows association rather than direction, both TCF12-to-partner and partner-to-TCF12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCF12 versus DCHS1 in UCEC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF12→partner) and Y-score (partner→TCF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DCHS1 →	+0.795	+0.189	<.001	.004	3	5
CCRCC	SCARF2 →	+0.626	+0.259	<.001	.002	3	5
LSCC	RCOR2 →	+0.998	+0.216	.001	.007	3	4
BRCA	RTTN →	+0.472	+0.325	.002	.006	3	4
LSCC	SHF →	+0.634	+0.347	<.001	<.001	3	4
LSCC	CSPG4 →	+0.835	+0.238	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,356 associations by consensus.

TCF12 vs DCHS1 — UCEC

Explore this scatter interactively →