TBXA2R

Across TCGA patient cohorts, TBXA2R mutation is significantly associated with the RNA expression of many other genes, with 1,264 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TBXA2R-associated genes across cancer lineages are MTFMT, KCTD9, and TIMM21. Each is linked with TBXA2R in more than 2 cancer types. Because this analysis shows association rather than direction, both TBXA2R-to-partner and partner-to-TBXA2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTFMT grouped by TBXA2R-low versus TBXA2R-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBXA2R→partner) and Y-score (partner→TBXA2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTFMT →	+0.489	+3.674	<.001	.001	3	3
UCEC	KCTD9 →	+0.748	+3.354	<.001	.005	3	3
UCEC	TIMM21 →	+0.629	+4.010	<.001	<.001	3	3
SKCM	SUPV3L1 →	+0.582	+3.341	.001	.005	3	3
SKCM	TIPIN →	+0.792	+3.207	<.001	.009	3	3
LUSC	RN7SL741P →	+0.179	+5.038	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,264 associations by consensus.

MTFMT by TBXA2R expression — UCEC

Explore this box plot interactively →