TBXA2R

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TBXA2R RNA expression is significantly associated with the go_rna of many other GO terms, with 3,896 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TBXA2R-associated GO terms across cancer lineages are Regulation of establishment of T cell polarity, Peptidyl-lysine oxidation, and Actin filament depolymerization. Each is linked with TBXA2R in more than 11 cancer types. Because this analysis shows association rather than direction, both TBXA2R-to-partner and partner-to-TBXA2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of establishment of T cell polarity grouped by TBXA2R-low versus TBXA2R-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBXA2R→partner) and Y-score (partner→TBXA2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASRegulation of establishment of T cell polarity →+0.220+0.643<.001.003312
URINARY_TRACTPeptidyl-lysine oxidation →+1.845+0.725<.001<.001311
URINARY_TRACTActin filament depolymerization →+0.194+0.980<.001<.001311
BONERegulation of focal adhesion assembly →+0.117+0.444.001.004310
LUNG_NSCLC_LUSCPositive regulation of establishment of T cell polarity →+0.275+0.912<.001<.001310
BONERegulation of cell-substrate junction assembly →+0.117+0.444.001.004310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,896 associations by consensus.

Regulation of establishment of T cell polarity by TBXA2R expression — PANCREAS

Box plot of Regulation of establishment of T cell polarity in TBXA2R-low vs TBXA2R-high samples in PANCREAS.

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Exploration