TBXA2R

Across TCGA cell cohorts, TBXA2R mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBXA2R-associated genes across cancer lineages are OR11H1, TCP11X2, and SUPT20HL1. Each is linked with TBXA2R in more than 1 cancer types. Because this analysis shows association rather than direction, both TBXA2R-to-partner and partner-to-TBXA2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by TBXA2R-low versus TBXA2R-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBXA2R→partner) and Y-score (partner→TBXA2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR11H1 →	+0.036	+4.700	.002	.002	3	1
OVARY	TCP11X2 →	+0.492	+4.228	<.001	.006	3	1
OVARY	SUPT20HL1 →	+0.092	+4.807	<.001	.003	3	1
LUNG_NSCLC_LUAD	AMER3 →	+0.447	+4.442	<.001	.004	3	1
LUNG_NSCLC_LUAD	PCARE →	+0.020	+4.343	.004	.002	3	1
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

OR11H1 by TBXA2R expression — OVARY

Explore this box plot interactively →