TBX4

Across TCGA patient cohorts, TBX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,893 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TBX4-associated proteins across cancer lineages are CGN_S329, REV3L, and RPL18A_S123. Each is linked with TBX4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBX4-to-partner and partner-to-TBX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX4 versus CGN_S329 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX4→partner) and Y-score (partner→TBX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CGN_S329 →	+1.208	+0.803	<.001	<.001	3	4
LSCC	REV3L →	+1.000	+0.832	<.001	.003	3	3
LUAD	RPL18A_S123 →	-0.496	-0.897	<.001	<.001	3	3
LUAD	STK39_T354 →	+0.488	+0.554	<.001	<.001	3	3
LUAD	CGN_S96 →	+0.984	+0.973	<.001	<.001	3	3
LUAD	DTNB →	+0.269	+0.509	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,893 associations by consensus.

TBX4 vs CGN_S329 — LUAD

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