TBX22

Across TCGA patient cohorts, TBX22 protein abundance is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBX22-associated genes across cancer lineages are HCK, CORO1A, and ESRP2. Each is linked with TBX22 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBX22-to-partner and partner-to-TBX22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX22 versus HCK in BRCA, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX22→partner) and Y-score (partner→TBX22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HCK →	+1.588	+2.903	.001	<.001	3	1
BRCA	CORO1A →	+1.284	+2.101	.005	.002	3	1
BRCA	ESRP2 →	-1.181	-2.551	.003	.007	3	1
BRCA	LILRB1 →	+1.678	+2.904	.002	<.001	3	1
BRCA	NKG7 →	+2.085	+2.647	.007	.005	3	1
BRCA	VSIR →	+0.961	+2.023	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

TBX22 vs HCK — BRCA

Explore this scatter interactively →