TBX21

Across TCGA patient cohorts, TBX21 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,670 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBX21-associated proteins across cancer lineages are RCSD1, ADA2, and DOCK10. Each is linked with TBX21 in more than 9 cancer types. Because this analysis shows association rather than direction, both TBX21-to-partner and partner-to-TBX21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX21 versus RCSD1 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX21→partner) and Y-score (partner→TBX21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RCSD1 →	+0.798	+0.736	<.001	<.001	3	10
LSCC	ADA2 →	+0.509	+0.591	<.001	<.001	3	10
LSCC	DOCK10 →	+0.553	+0.753	<.001	<.001	3	10
OV	TBC1D10C →	+0.865	+0.631	<.001	<.001	3	9
BRCA	WAS →	+0.521	+0.923	<.001	<.001	3	9
BRCA	APOL3 →	+0.836	+0.913	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,670 associations by consensus.

TBX21 vs RCSD1 — OV

Explore this scatter interactively →