TBX2

Across TCGA patient cohorts, TBX2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,472 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TBX2-associated genes across cancer lineages are RIPOR2, FOXP1, and CRY2. Each is linked with TBX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBX2-to-partner and partner-to-TBX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX2 versus RIPOR2 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX2→partner) and Y-score (partner→TBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIPOR2 →	+0.914	+0.379	<.001	<.001	3	4
OV	FOXP1 →	+0.440	+0.607	.004	.001	3	4
CCRCC	CRY2 →	+0.748	+0.561	<.001	<.001	3	4
LUAD	RHOJ →	+0.667	+0.443	<.001	<.001	3	4
OV	LRRC4B →	+0.679	+0.691	.003	.004	3	4
CCRCC	ROBO4 →	+0.784	+0.486	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,472 associations by consensus.

TBX2 vs RIPOR2 — LSCC

Explore this scatter interactively →