TBX19

Across TCGA patient cohorts, TBX19 mutation is significantly associated with the RNA expression of many other genes, with 2,356 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBX19-associated genes across cancer lineages are BNIP3P41, MIRLET7A1, and MTRES1P1. Each is linked with TBX19 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBX19-to-partner and partner-to-TBX19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by TBX19-low versus TBX19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX19→partner) and Y-score (partner→TBX19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BNIP3P41 →	+0.008	+3.723	<.001	.008	3	3
HNSC	MIRLET7A1 →	+0.911	+3.698	<.001	.007	3	2
COAD	MTRES1P1 →	+0.159	+3.942	<.001	.002	3	2
LIHC	LINC01911 →	+0.069	+7.495	<.001	<.001	3	2
LIHC	RPL32P30 →	+0.149	+5.186	<.001	.007	3	2
UCEC	RNF182 →	-0.752	-1.906	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,356 associations by consensus.

BNIP3P41 by TBX19 expression — UCEC

Explore this box plot interactively →