TBX19

Across TCGA cell cohorts, TBX19 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TBX19-associated genes across cancer lineages are LILRB2, OR5T1, and ETNPPL. Each is linked with TBX19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBX19-to-partner and partner-to-TBX19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRB2 grouped by TBX19-low versus TBX19-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX19→partner) and Y-score (partner→TBX19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	LILRB2 →	+0.023	+4.095	.004	.009	3	1
SKIN	OR5T1 →	+0.014	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ETNPPL →	+0.189	+3.021	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LILRB2 by TBX19 expression — SKIN

Explore this box plot interactively →