TBX15

Across TCGA cell cohorts, TBX15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,140 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TBX15-associated GO terms across cancer lineages are Neuropilin signaling pathway, Response to activity, and Positive regulation of post-translational protein modification. Each is linked with TBX15 in more than 6 cancer types. Because this analysis shows association rather than direction, both TBX15-to-partner and partner-to-TBX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuropilin signaling pathway grouped by TBX15-low versus TBX15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX15→partner) and Y-score (partner→TBX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Neuropilin signaling pathway →	+0.190	+2.374	.003	<.001	3	7
BONE	Response to activity →	+0.100	+2.752	<.001	<.001	3	6
BONE	Positive regulation of post-translational protein modification →	+0.064	+2.913	.002	<.001	3	6
BONE	Positive regulation of protein modification by small protein conjugation or removal →	+0.056	+2.413	.002	<.001	3	6
CNS	Motor neuron migration →	+0.248	+1.796	<.001	<.001	3	6
BLOOD_Myeloma	Inorganic cation import across plasma membrane →	-0.048	-0.137	.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,140 associations by consensus.

Neuropilin signaling pathway by TBX15 expression — BONE

Explore this box plot interactively →