TBX10

Across TCGA patient cohorts, TBX10 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,372 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBX10-associated proteins across cancer lineages are CARD6, CDC73, and CPSF7. Each is linked with TBX10 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBX10-to-partner and partner-to-TBX10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBX10 versus CARD6 in LSCC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBX10→partner) and Y-score (partner→TBX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CARD6 →	-0.424	-0.362	<.001	.003	3	3
LSCC	CDC73 →	+0.227	+0.358	<.001	<.001	3	3
GBM	CPSF7 →	+0.312	+0.219	<.001	.001	3	3
LSCC	DHX16 →	+0.200	+0.343	<.001	<.001	3	3
LSCC	GTF3C3 →	+0.270	+0.356	<.001	<.001	3	3
HNSC	HOMER3 →	-0.376	-0.369	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,372 associations by consensus.

TBX10 vs CARD6 — LSCC

Explore this scatter interactively →