TBRG4

Across TCGA pan-cancer cohorts, TBRG4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TBRG4 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher TBRG4 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TBRG4 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

GBM, LSCC, and HNSC are the cancer types where TBRG4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.675	0.282	.005	22	view →
LSCC	DFS	Quartile	II,III,IV	0.933	0.440	.005	20	view →
HNSC	OS	Median	All	1.000	0.961	.030	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TBRG4–GBM (OS)

Open the GBM breakdown →