TBRG4

Across TCGA cell cohorts, TBRG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,434 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TBRG4-associated GO terms across cancer lineages are 2-oxoglutarate decarboxylation to succinyl-CoA, Transcription initiation at RNA polymerase I promoter, and Positive regulation of isotype switching to IgG isotypes. Each is linked with TBRG4 in more than 17 cancer types. Because this analysis shows association rather than direction, both TBRG4-to-partner and partner-to-TBRG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 2-oxoglutarate decarboxylation to succinyl-CoA grouped by TBRG4-low versus TBRG4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBRG4→partner) and Y-score (partner→TBRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.145	+1.036	<.001	<.001	3	18
OESOPHAGUS	Transcription initiation at RNA polymerase I promoter →	+0.158	+1.020	<.001	<.001	3	17
STOMACH	Positive regulation of isotype switching to IgG isotypes →	+0.143	+0.698	.002	.006	3	16
SOFT_TISSUE	Ribosomal large subunit assembly →	+0.113	+0.892	<.001	<.001	3	15
PANCREAS	Transcription by RNA polymerase I →	+0.110	+0.820	<.001	<.001	3	15
SOFT_TISSUE	Pre-mRNA catabolic process →	+0.167	+1.004	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,434 associations by consensus.

2-oxoglutarate decarboxylation to succinyl-CoA by TBRG4 expression — URINARY_TRACT

Explore this box plot interactively →