TBPL1

Across TCGA cell cohorts, TBPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,164 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible TBPL1-associated genes across cancer lineages are BAG1, KLHL12, and MED30. Each is linked with TBPL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBPL1-to-partner and partner-to-TBPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBPL1 versus BAG1 in BREAST, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBPL1→partner) and Y-score (partner→TBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	BAG1 →	-1.153	-1.248	.002	<.001	3	4
LIVER	KLHL12 →	+0.835	+1.170	.001	.004	3	4
LARGE_INTESTINE	MED30 →	+0.590	+0.679	.001	.004	3	4
BLOOD_Leukemia	METAP1D →	+0.632	+0.622	<.001	<.001	3	3
LUNG_NSCLC_LUAD	UST →	-0.950	-0.867	.008	.001	3	3
LUNG_NSCLC_LUAD	ZNF160 →	-0.776	-0.601	.007	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,164 associations by consensus.

TBPL1 vs BAG1 — BREAST

Explore this scatter interactively →