TBL1Y

Across TCGA patient cohorts, TBL1Y protein abundance is significantly associated with the RNA expression of many other genes, with 1,899 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBL1Y-associated genes across cancer lineages are LMLN, FAM47E, and TTC30B. Each is linked with TBL1Y in more than 1 cancer types. Because this analysis shows association rather than direction, both TBL1Y-to-partner and partner-to-TBL1Y results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBL1Y versus LMLN in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL1Y→partner) and Y-score (partner→TBL1Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LMLN →	-0.601	-0.754	.004	.008	3	2
BRCA	FAM47E →	-1.003	-0.838	.003	.004	3	2
BRCA	TTC30B →	-0.681	-0.810	<.001	.004	3	2
BRCA	ALOX12 →	-1.067	-0.997	<.001	.008	3	2
BRCA	LNPEP →	-0.840	-0.942	<.001	<.001	3	2
BRCA	SRR →	-0.681	-0.739	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,899 associations by consensus.

TBL1Y vs LMLN — BRCA

Explore this scatter interactively →