TBL1XR1-AS1

Across TCGA pan-cancer cohorts, TBL1XR1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TBL1XR1-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TBL1XR1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TBL1XR1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LIHC show a favorable association.

BRCA, UVM, and UCEC are the cancer types where TBL1XR1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	III,IV	0.604	0.378	.001	67	view →
UVM	OS	Tertile	All	0.339	0.820	<.001	40	view →
UCEC	DFS	Tertile	All	0.612	0.837	<.001	38	view →
KIRP	OS	Tertile	II,III,IV	0.339	0.672	.016	31	view →
LGG	DFS	Median	All	0.781	0.869	<.001	30	view →
STAD	DFS	Quartile	IV	0.169	0.704	.002	26	view →
THCA	OS	Tertile	II,III,IV	0.905	0.987	.014	20	view →
PAAD	OS	Median	All	0.257	0.502	.003	18	view →
KIRC	DFS	Median	All	0.767	0.845	.019	14	view →
ACC	OS	Quartile	All	0.348	0.684	.002	13	view →
LIHC	OS	Quartile	III,IV	0.984	0.588	.006	13	view →
UCS	OS	Quartile	II,III,IV	0.600	0.248	.023	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TBL1XR1-AS1–BRCA (DFS)

Open the BRCA breakdown →