TBL1X

Across TCGA cell cohorts, TBL1X RNA expression is significantly associated with the go_rna of many other GO terms, with 2,767 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBL1X-associated GO terms across cancer lineages are Negative regulation of heterochromatin organization, Negative regulation of heterochromatin formation, and Positive regulation of organelle assembly. Each is linked with TBL1X in more than 8 cancer types. Because this analysis shows association rather than direction, both TBL1X-to-partner and partner-to-TBL1X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of heterochromatin organization grouped by TBL1X-low versus TBL1X-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBL1X→partner) and Y-score (partner→TBL1X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of heterochromatin organization →	+0.078	+0.839	<.001	.002	3	9
SOFT_TISSUE	Negative regulation of heterochromatin formation →	+0.078	+0.839	<.001	.002	3	9
LARGE_INTESTINE	Positive regulation of organelle assembly →	+0.063	+1.374	<.001	<.001	3	9
SOFT_TISSUE	Nucleosome assembly →	+0.068	+1.066	<.001	<.001	3	8
OESOPHAGUS	Copper ion export →	-0.176	-1.207	.004	.007	3	8
BONE	Random inactivation of X chromosome →	+0.104	+0.703	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,767 associations by consensus.

Negative regulation of heterochromatin organization by TBL1X expression — SOFT_TISSUE

Explore this box plot interactively →