TBCEL

Across TCGA patient cohorts, TBCEL mutation is significantly associated with the RNA expression of many other genes, with 321 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBCEL-associated genes across cancer lineages are COX6CP12, RN7SL248P, and RNU6-839P. Each is linked with TBCEL in more than 2 cancer types. Because this analysis shows association rather than direction, both TBCEL-to-partner and partner-to-TBCEL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6CP12 grouped by TBCEL-low versus TBCEL-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCEL→partner) and Y-score (partner→TBCEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	COX6CP12 →	+0.098	+3.513	<.001	.004	3	3
UCEC	RN7SL248P →	+0.086	+3.722	<.001	.001	3	3
BRCA	RNU6-839P →	+0.259	+8.471	<.001	.005	3	2
STAD	OR4P4 →	+0.148	+4.035	<.001	.004	3	2
STAD	RN7SKP39 →	+0.282	+4.434	<.001	.002	3	2
STAD	RN7SKP46 →	+0.487	+3.691	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 321 associations by consensus.

COX6CP12 by TBCEL expression — SKCM

Explore this box plot interactively →