TBCE

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TBCE protein abundance is significantly associated with the RNA expression of many other genes, with 1,884 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBCE-associated genes across cancer lineages are COX7A2L, FMO4, and SMARCB1. Each is linked with TBCE in more than 4 cancer types. Because this analysis shows association rather than direction, both TBCE-to-partner and partner-to-TBCE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBCE versus COX7A2L in BLOOD_Myeloma, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCE→partner) and Y-score (partner→TBCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaCOX7A2L →+0.951+0.609.007.00735
SOFT_TISSUEFMO4 →-1.644-1.170.002<.00134
OVARYSMARCB1 →+0.901+1.000<.001.00334
BLOOD_LymphomaRTL8C →+2.946+0.614<.001.00634
BLOOD_LymphomaLAMTOR4 →-0.722-0.727.007.00934
LUNG_SCLCCFAP69 →-0.946-0.668.005.00734
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,884 associations by consensus.

TBCE vs COX7A2L — BLOOD_Myeloma

Per-sample scatter of TBCE vs COX7A2L in BLOOD_Myeloma (Pearson r = 0.39).

Explore this scatter interactively →

Exploration