TBCCD1

Across TCGA patient cohorts, TBCCD1 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBCCD1-associated genes across cancer lineages are CD8+ T-cells, pDC, and Preadipocytes. Each is linked with TBCCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBCCD1-to-partner and partner-to-TBCCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by TBCCD1-low versus TBCCD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCCD1→partner) and Y-score (partner→TBCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.022	+2.385	<.001	.012	3	2
UCEC	pDC →	+0.076	+2.491	<.001	.010	3	2
COAD	Preadipocytes →	+0.089	+5.754	<.001	<.001	3	1
COAD	Tregs →	+0.039	+5.087	<.001	.002	3	1
COAD	CD4+ T-cells →	+0.021	+5.156	<.001	.032	3	1
UCEC	Endothelial cells →	-0.044	-3.300	.009	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CD8+ T-cells by TBCCD1 expression — UCEC

Explore this box plot interactively →