TBCC

Across TCGA patient cohorts, TBCC mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBCC-associated genes across cancer lineages are Th2 cells and Neutrophils. Each is linked with TBCC in more than 1 cancer types. Because this analysis shows association rather than direction, both TBCC-to-partner and partner-to-TBCC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by TBCC-low versus TBCC-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCC→partner) and Y-score (partner→TBCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Th2 cells →	+0.378	+2.815	<.001	.036	3	2
UCEC	Neutrophils →	+0.021	+2.166	<.001	.040	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Th2 cells by TBCC expression — UCEC

Explore this box plot interactively →