TBCAP3

Across TCGA patient cohorts, TBCAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,590 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TBCAP3-associated GO terms across cancer lineages are U2-type prespliceosome assembly, U4 snRNA 3'-end processing, and Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Each is linked with TBCAP3 in more than 17 cancer types. Because this analysis shows association rather than direction, both TBCAP3-to-partner and partner-to-TBCAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U2-type prespliceosome assembly grouped by TBCAP3-low versus TBCAP3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBCAP3→partner) and Y-score (partner→TBCAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	U2-type prespliceosome assembly →	+0.067	+0.220	<.001	<.001	3	18
STAD	U4 snRNA 3'-end processing →	+0.043	+0.241	<.001	<.001	3	17
STAD	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.045	+0.254	<.001	<.001	3	16
STAD	Mitochondrial gene expression →	+0.053	+0.224	<.001	<.001	3	16
STAD	Signal transduction in response to DNA damage →	+0.051	+0.177	<.001	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.043	+0.172	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,590 associations by consensus.

U2-type prespliceosome assembly by TBCAP3 expression — STAD

Explore this box plot interactively →