TBCAP3

Across TCGA pan-cancer cohorts, TBCAP3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TBCAP3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TBCAP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TBCAP3 is over-expressed in tumor, although a few such as PAAD and STAD show the opposite, repressed pattern.

LUSC, HNSC, and PAAD are the cancer types where TBCAP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TBCAP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	III,IV	+0.439	.022	4	view →
HNSC	Male	All	+0.234	.003	3	view →
PAAD	Male	All	−0.635	.007	2	view →
STAD	Male	All	−0.237	.039	1	view →
KIRP	Male	II,III,IV	−0.214	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TBCAP3–LUSC

Open the LUSC breakdown →