TBC1D9

Across TCGA cell cohorts, TBC1D9 mutation is significantly associated with the RNA expression of many other genes, with 780 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBC1D9-associated genes across cancer lineages are OR2L8, TTC5, and CGRRF1. Each is linked with TBC1D9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D9-to-partner and partner-to-TBC1D9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L8 grouped by TBC1D9-low versus TBC1D9-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D9→partner) and Y-score (partner→TBC1D9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	OR2L8 →	+0.046	+4.807	<.001	.006	3	2
BLOOD_Leukemia	TTC5 →	+0.775	+3.169	<.001	.008	3	2
LARGE_INTESTINE	CGRRF1 →	+0.482	+2.640	.001	<.001	3	2
LARGE_INTESTINE	UFSP2 →	+0.441	+1.807	.001	.005	3	2
LARGE_INTESTINE	C12orf57 →	+0.886	+1.969	<.001	<.001	3	2
LARGE_INTESTINE	TTC33 →	+0.693	+1.969	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 780 associations by consensus.

OR2L8 by TBC1D9 expression — BLOOD_Myeloma

Explore this box plot interactively →