TBC1D8B

Across TCGA pan-cancer cohorts, TBC1D8B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TBC1D8B data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TBC1D8B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D8B expression acts as an unfavorable survival marker.

CCRCC, HNSC, and LSCC are the cancer types where TBC1D8B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.595	0.880	.001	61	view →
HNSC	OS	Tertile	All	0.634	0.856	.015	15	view →
LSCC	DFS	Quartile	All	0.615	0.930	.004	12	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LUAD	DFS	Median	All	0.669	0.950	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TBC1D8B–CCRCC (DFS)

Open the CCRCC breakdown →