TBC1D8B

Across TCGA cell cohorts, TBC1D8B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,490 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TBC1D8B-associated GO terms across cancer lineages are Golgi vesicle transport, Protein targeting, and SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Each is linked with TBC1D8B in more than 12 cancer types. Because this analysis shows association rather than direction, both TBC1D8B-to-partner and partner-to-TBC1D8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by TBC1D8B-low versus TBC1D8B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D8B→partner) and Y-score (partner→TBC1D8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Golgi vesicle transport →	+0.056	+1.236	<.001	.001	2	13
SOFT_TISSUE	Protein targeting →	+0.062	+1.536	<.001	<.001	3	12
BONE	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.126	+1.514	<.001	<.001	3	12
BONE	Viral process →	+0.104	+1.362	<.001	<.001	3	11
SOFT_TISSUE	Protein localization to lysosome →	+0.066	+1.551	.003	.001	2	12
SOFT_TISSUE	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.065	+1.561	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,490 associations by consensus.

Golgi vesicle transport by TBC1D8B expression — BONE

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