Across TCGA patient cohorts, TBC1D8 RNA expression is significantly associated with the RNA expression of many other genes, with 20,024 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TBC1D8-associated genes across cancer lineages are MAP3K2, ATXN1L, and EP300. Each is linked with TBC1D8 in more than 33 cancer types. Because this analysis shows association rather than direction, both TBC1D8-to-partner and partner-to-TBC1D8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D8→partner) and Y-score (partner→TBC1D8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	MAP3K2 →	+1.418	+1.041	<.001	<.001	3	34
DLBC	ATXN1L →	+1.193	+1.249	<.001	<.001	3	33
DLBC	EP300 →	+1.205	+1.249	.001	<.001	3	33
UVM	NUFIP2 →	+1.018	+1.010	<.001	<.001	3	33
SCLC	BICRAL →	+1.378	+1.381	<.001	<.001	3	33
UVM	BIRC6 →	+1.145	+0.876	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,024 associations by consensus.

Exploration

TBC1D8 survival (RNA) · tumor vs normal (RNA) · all TBC1D8 data types