Across TCGA patient cohorts, TBC1D8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,624 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBC1D8-associated proteins across cancer lineages are PALMD, TYROBP, and PHF2. Each is linked with TBC1D8 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D8-to-partner and partner-to-TBC1D8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D8→partner) and Y-score (partner→TBC1D8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PALMD →	+0.374	+0.564	<.001	<.001	3	4
BRCA	TYROBP →	-0.630	-0.689	.002	.005	3	4
CCRCC	PHF2 →	+0.182	+0.363	.001	.001	3	4
BRCA	RIPK2 →	-0.321	-0.751	<.001	<.001	3	4
HNSC	ATP1B1 →	+0.524	+0.827	.002	.003	3	4
PDAC	SOX13 →	+0.485	+0.650	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,624 associations by consensus.

Exploration

TBC1D8 survival (RNA) · tumor vs normal (RNA) · all TBC1D8 data types