Across TCGA patient cohorts, TBC1D8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,097 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TBC1D8-associated genes across cancer lineages are FAM72B, ST6GALNAC1, and DNA2. Each is linked with TBC1D8 in more than 4 cancer types. Because this analysis shows association rather than direction, both TBC1D8-to-partner and partner-to-TBC1D8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D8→partner) and Y-score (partner→TBC1D8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM72B →	-0.764	-0.381	.001	<.001	3	5
LSCC	ST6GALNAC1 →	+1.664	+0.321	<.001	<.001	3	5
UCEC	DNA2 →	-0.657	-0.306	<.001	.007	3	5
GBM	ZGRF1 →	-0.485	-0.490	.003	<.001	3	5
GBM	DIAPH3 →	-0.717	-0.448	<.001	<.001	3	5
LUAD	NUF2 →	-0.999	-0.288	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,097 associations by consensus.

Exploration

TBC1D8 survival (RNA) · tumor vs normal (RNA) · all TBC1D8 data types