Across TCGA cell cohorts, TBC1D8 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TBC1D8-associated genes across cancer lineages are C20orf85, OR1L4, and OR4D6. Each is linked with TBC1D8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D8-to-partner and partner-to-TBC1D8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D8→partner) and Y-score (partner→TBC1D8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C20orf85 →	+0.086	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR1L4 →	+0.053	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR4D6 →	+0.035	+4.977	<.001	.002	3	1
SOFT_TISSUE	MMP26 →	+0.086	+5.169	<.001	<.001	3	1
SOFT_TISSUE	OR51L1 →	+0.027	+4.369	<.001	.008	3	1
SOFT_TISSUE	OR51G2 →	+0.027	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

TBC1D8 survival (RNA) · tumor vs normal (RNA) · all TBC1D8 data types