TBC1D8-AS1

Across TCGA pan-cancer cohorts, TBC1D8-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TBC1D8-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TBC1D8-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TBC1D8-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, UCS, and LIHC are the cancer types where TBC1D8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	II,III,IV	0.670	0.491	<.001	93	view →
UCS	DFS	Tertile	III,IV	0.593	0.175	.001	64	view →
LIHC	DFS	Tertile	All	0.443	0.612	<.001	54	view →
ACC	DFS	Tertile	II,III,IV	0.119	0.651	.002	45	view →
KIRP	DFS	Tertile	IV	0.046	0.529	.010	31	view →
UVM	DFS	Quartile	All	0.826	0.375	.006	28	view →
MESO	DFS	Median	II,III,IV	0.228	0.672	<.001	27	view →
CHOL	DFS	Tertile	All	0.614	0.108	.005	18	view →
OV	DFS	Tertile	IV	0.431	0.243	.030	18	view →
READ	OS	Median	IV	0.824	0.455	.005	18	view →
THCA	OS	Median	IV	0.584	1.000	.008	16	view →
ESCA	DFS	Quartile	III,IV	0.203	0.467	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TBC1D8-AS1–BRCA (OS)

Open the BRCA breakdown →