TBC1D7

Across TCGA cell cohorts, TBC1D7 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TBC1D7-associated genes across cancer lineages are CCDC182, LYZL2, and GRIFIN. Each is linked with TBC1D7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D7-to-partner and partner-to-TBC1D7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC182 grouped by TBC1D7-low versus TBC1D7-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D7→partner) and Y-score (partner→TBC1D7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CCDC182 →	+0.033	+5.285	<.001	.003	3	1
LUNG_SCLC	LYZL2 →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	GRIFIN →	+0.117	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCDC182 by TBC1D7 expression — STOMACH

Explore this box plot interactively →