TBC1D3P5

Across TCGA patient cohorts, TBC1D3P5 mutation is significantly associated with the RNA expression of many other genes, with 1,230 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D3P5-associated genes across cancer lineages are PPP1R26P4, MTATP6P21, and LINC00265-2P. Each is linked with TBC1D3P5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3P5-to-partner and partner-to-TBC1D3P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R26P4 grouped by TBC1D3P5-low versus TBC1D3P5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3P5→partner) and Y-score (partner→TBC1D3P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R26P4 →	+0.007	+4.341	<.001	.009	3	2
HNSC	MTATP6P21 →	+0.553	+5.241	<.001	.007	3	2
READ	LINC00265-2P →	+0.110	+5.653	<.001	.003	3	2
READ	RN7SL726P →	+0.266	+6.257	<.001	.001	3	2
LUSC	RNA5SP281 →	+0.375	+5.625	<.001	.004	3	2
BRCA	SNRPEP7 →	+0.256	+3.875	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,230 associations by consensus.

PPP1R26P4 by TBC1D3P5 expression — BRCA

Explore this box plot interactively →