TBC1D3L

Across TCGA patient cohorts, TBC1D3L RNA expression is significantly associated with the go_rna of many other GO terms, with 7,157 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TBC1D3L-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Positive regulation of DNA repair, and Base-excision repair, AP site formation. Each is linked with TBC1D3L in more than 22 cancer types. Because this analysis shows association rather than direction, both TBC1D3L-to-partner and partner-to-TBC1D3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by TBC1D3L-low versus TBC1D3L-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3L→partner) and Y-score (partner→TBC1D3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Positive regulation of double-strand break repair →	+0.040	+0.421	<.001	<.001	3	23
KIRC	Positive regulation of DNA repair →	+0.038	+0.487	<.001	<.001	3	22
KIRP	Base-excision repair, AP site formation →	+0.074	+0.711	<.001	<.001	3	21
STAD	Positive regulation of DNA metabolic process →	+0.035	+0.168	.002	<.001	3	20
KIRC	Regulation of DNA repair →	+0.031	+0.415	<.001	<.001	3	19
UVM	Mitochondrial gene expression →	+0.040	+0.388	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,157 associations by consensus.

Positive regulation of double-strand break repair by TBC1D3L expression — UVM

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