TBC1D3L

Across TCGA pan-cancer cohorts, TBC1D3L RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TBC1D3L data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TBC1D3L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TBC1D3L expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

KIRC, BLCA, and ACC are the cancer types where TBC1D3L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.558	0.693	<.001	104	view →
BLCA	DFS	Tertile	All	0.571	0.446	.006	64	view →
ACC	OS	Tertile	All	0.398	0.795	.007	62	view →
LIHC	DFS	Median	All	0.459	0.641	<.001	39	view →
PRAD	DFS	Median	All	0.662	0.880	<.001	30	view →
SKCM	DFS	Quartile	III,IV	0.661	0.370	.005	24	view →
BRCA	OS	Median	IV	0.796	0.382	.004	21	view →
DLBC	DFS	Tertile	III,IV	1.000	0.425	.022	15	view →
CHOL	OS	Quartile	All	0.861	0.145	.014	12	view →
MESO	DFS	Median	III,IV	0.276	0.468	.006	12	view →
STAD	OS	Quartile	III,IV	0.795	0.390	.016	9	view →
THYM	DFS	Median	III,IV	0.386	1.000	.002	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TBC1D3L–KIRC (OS)

Open the KIRC breakdown →