TBC1D3L

Across TCGA cell cohorts, TBC1D3L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,793 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBC1D3L-associated GO terms across cancer lineages are Target-directed miRNA degradation, Cilium movement, and Positive regulation of G2/MI transition of meiotic cell cycle. Each is linked with TBC1D3L in more than 10 cancer types. Because this analysis shows association rather than direction, both TBC1D3L-to-partner and partner-to-TBC1D3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Target-directed miRNA degradation grouped by TBC1D3L-low versus TBC1D3L-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3L→partner) and Y-score (partner→TBC1D3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Target-directed miRNA degradation →	+0.131	+1.997	<.001	<.001	3	11
BONE	Cilium movement →	-0.094	-1.280	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of G2/MI transition of meiotic cell cycle →	-0.132	-1.159	<.001	<.001	3	10
LUNG_SCLC	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.057	+1.090	.004	.001	3	10
LARGE_INTESTINE	mRNA splice site recognition →	+0.099	+1.482	<.001	<.001	3	10
BONE	Cilium or flagellum-dependent cell motility →	-0.102	-1.140	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,793 associations by consensus.

Target-directed miRNA degradation by TBC1D3L expression — URINARY_TRACT

Explore this box plot interactively →