TBC1D3K

Across TCGA pan-cancer cohorts, TBC1D3K RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated TBC1D3K data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TBC1D3K RNA is associated with better overall survival. In most high-consensus cancer types, elevated TBC1D3K expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, MESO, and OV are the cancer types where TBC1D3K RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.517	0.321	.006	86	view →
MESO	OS	Tertile	All	0.169	0.661	<.001	51	view →
OV	OS	Tertile	III,IV	0.777	0.852	.011	48	view →
UVM	OS	Tertile	All	0.274	0.720	<.001	36	view →
ACC	DFS	Tertile	All	0.216	0.657	.023	27	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	21	view →
HNSC	OS	Tertile	IV	0.365	0.667	.033	21	view →
SKCM	DFS	Tertile	IV	0.943	0.159	.031	9	view →
SARC	OS	Tertile	All	0.663	0.871	.016	9	view →
CHOL	DFS	Tertile	All	0.798	0.298	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

TBC1D3K–BLCA (OS)

Open the BLCA breakdown →