TBC1D3K

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TBC1D3K RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TBC1D3K’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where TBC1D3K RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TBC1D3K is over-expressed in tumor.

KIRP and KIRC are the cancer types where TBC1D3K tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TBC1D3K RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRPFemaleAll+0.024.0431view →
KIRCAllAll+0.007.0271view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TBC1D3K–KIRP

Tumor-vs-normal expression box plot for TBC1D3K RNA in KIRP.

Open the KIRP breakdown →

Exploration