Across TCGA pan-cancer cohorts, TBC1D3I Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TBC1D3I data layer compared with 10 for mass-spec protein.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TBC1D3I Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TBC1D3I expression acts as an unfavorable survival marker.
LUAD are the cancer types where TBC1D3I Mutation most reproducibly stratifies survival.