TBC1D3H

Across TCGA patient cohorts, TBC1D3H RNA expression is significantly associated with the go_rna of many other GO terms, with 4,110 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TBC1D3H-associated GO terms across cancer lineages are Regulation of DNA recombination, Nucleotide-excision repair, and Methylation. Each is linked with TBC1D3H in more than 7 cancer types. Because this analysis shows association rather than direction, both TBC1D3H-to-partner and partner-to-TBC1D3H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA recombination grouped by TBC1D3H-low versus TBC1D3H-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3H→partner) and Y-score (partner→TBC1D3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA recombination →	+0.073	+0.008	<.001	<.001	3	8
STAD	Nucleotide-excision repair →	+0.069	+0.005	<.001	<.001	3	8
STAD	Methylation →	+0.074	+0.006	<.001	<.001	3	7
STAD	Positive regulation of DNA repair →	+0.080	+0.005	<.001	<.001	3	7
SCLC	Negative regulation of cell projection organization →	+0.061	+0.321	<.001	<.001	3	7
STAD	Regulation of protein ubiquitination →	+0.090	+0.005	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,110 associations by consensus.

Regulation of DNA recombination by TBC1D3H expression — STAD

Explore this box plot interactively →