TBC1D3H

Across TCGA pan-cancer cohorts, TBC1D3H RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated TBC1D3H data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher TBC1D3H RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D3H expression acts as an unfavorable survival marker, although some lineages such as SKCM and SCLC show a favorable association.

READ, KIRP, and KIRC are the cancer types where TBC1D3H RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	III,IV	0.101	0.756	<.001	72	view →
KIRP	OS	Tertile	II,III,IV	0.109	0.590	<.001	39	view →
KIRC	DFS	Tertile	III,IV	0.155	0.478	.004	36	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	27	view →
LAML	DFS	Tertile	All	0.363	0.590	.026	18	view →
GBM	OS	Tertile	All	0.101	0.421	.009	9	view →
SKCM	DFS	Tertile	III,IV	1.000	0.469	.041	6	view →
SCLC	OS	Quartile	All	0.659	0.174	<.001	6	view →
BLCA	OS	Tertile	III,IV	0.823	0.348	.036	6	view →
LUSC	DFS	Tertile	All	0.479	0.653	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

TBC1D3H–READ (DFS)

Open the READ breakdown →