TBC1D3G

Across TCGA pan-cancer cohorts, TBC1D3G RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TBC1D3G data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TBC1D3G RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TBC1D3G expression acts as an unfavorable survival marker, although some lineages such as MESO and GBM show a favorable association.

OV, UCEC, and LUSC are the cancer types where TBC1D3G RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Quartile	III,IV	0.599	0.715	.004	64	view →
UCEC	DFS	Tertile	IV	0.185	0.750	<.001	48	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	37	view →
CESC	OS	Tertile	IV	0.164	0.612	.013	36	view →
UCS	OS	Tertile	III,IV	0.298	0.634	.022	36	view →
COAD	OS	Tertile	III,IV	0.615	0.796	.020	33	view →
KIRC	DFS	Tertile	IV	0.331	0.640	.014	30	view →
SKCM	OS	Tertile	III,IV	0.390	0.752	.010	18	view →
BRCA	DFS	Tertile	II,III,IV	0.397	0.540	.012	18	view →
DLBC	OS	Tertile	All	0.526	0.936	.002	18	view →
HNSC	OS	Tertile	III,IV	0.492	0.644	.018	18	view →
STAD	DFS	Quartile	All	0.500	0.666	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TBC1D3G–OV (OS)

Open the OV breakdown →