TBC1D3E

Across TCGA patient cohorts, TBC1D3E RNA expression is significantly associated with the go_rna of many other GO terms, with 4,837 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TBC1D3E-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, Positive regulation of DNA metabolic process, and Regulation of RNA splicing. Each is linked with TBC1D3E in more than 13 cancer types. Because this analysis shows association rather than direction, both TBC1D3E-to-partner and partner-to-TBC1D3E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alternative mRNA splicing, via spliceosome grouped by TBC1D3E-low versus TBC1D3E-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3E→partner) and Y-score (partner→TBC1D3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Alternative mRNA splicing, via spliceosome →	+0.044	+0.070	<.001	<.001	3	14
STAD	Positive regulation of DNA metabolic process →	+0.057	+0.092	<.001	<.001	3	14
STAD	Regulation of RNA splicing →	+0.064	+0.104	<.001	<.001	3	14
DLBC	Positive regulation of stem cell population maintenance →	+0.035	+0.062	.004	<.001	3	13
DLBC	Peptidyl-lysine acetylation →	+0.048	+0.059	<.001	<.001	3	13
GBM	Obsolete histone H3-K4 methylation →	+0.061	+0.127	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,837 associations by consensus.

Alternative mRNA splicing, via spliceosome by TBC1D3E expression — STAD

Explore this box plot interactively →