TBC1D3E

Across TCGA pan-cancer cohorts, TBC1D3E RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated TBC1D3E data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher TBC1D3E RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D3E expression acts as an unfavorable survival marker, although some lineages such as BLCA and CHOL show a favorable association.

STAD, BLCA, and KICH are the cancer types where TBC1D3E RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	II,III,IV	0.265	0.489	<.001	74	view →
BLCA	OS	Tertile	All	0.693	0.532	.001	55	view →
KICH	DFS	Tertile	III,IV	0.353	0.834	.002	22	view →
PRAD	DFS	Median	All	0.646	0.897	<.001	22	view →
CHOL	OS	Median	All	0.812	0.435	.007	19	view →
COAD	OS	Quartile	All	0.924	0.751	.011	18	view →
LGG	DFS	Quartile	All	0.308	0.441	.006	14	view →
DLBC	OS	Tertile	All	0.721	0.948	.020	12	view →
CESC	DFS	Quartile	III,IV	0.517	0.781	.019	12	view →
UCS	DFS	Quartile	II,III,IV	0.706	0.225	.030	12	view →
KIRC	DFS	Median	All	0.562	0.722	.006	11	view →
ACC	DFS	Median	IV	0.518	0.122	.021	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

TBC1D3E–STAD (DFS)

Open the STAD breakdown →