TBC1D31

Across TCGA pan-cancer cohorts, TBC1D31 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TBC1D31 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TBC1D31 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TBC1D31 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where TBC1D31 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.984	0.752	<.001	42	view →
PDAC	OS	Median	All	0.649	0.371	.004	29	view →
LSCC	DFS	Tertile	All	1.000	0.955	.020	5	view →
HNSC	DFS	Tertile	III,IV	0.703	0.962	.017	3	view →
UCEC	OS	Tertile	All	0.904	1.000	.029	2	view →
GBM	OS	Tertile	All	0.347	0.634	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TBC1D31–LUAD (DFS)

Open the LUAD breakdown →