TBC1D31

Across TCGA cell cohorts, TBC1D31 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,031 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D31-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Regulation of mitotic sister chromatid separation, and Protein localization to kinetochore. Each is linked with TBC1D31 in more than 18 cancer types. Because this analysis shows association rather than direction, both TBC1D31-to-partner and partner-to-TBC1D31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by TBC1D31-low versus TBC1D31-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D31→partner) and Y-score (partner→TBC1D31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to condensed chromosome →	+0.194	+1.023	.001	<.001	3	19
BREAST	Regulation of mitotic sister chromatid separation →	+0.146	+0.935	<.001	.002	3	18
OESOPHAGUS	Protein localization to kinetochore →	+0.193	+0.881	<.001	.001	3	18
STOMACH	Nuclear chromosome segregation →	+0.119	+1.399	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.147	+0.949	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid segregation →	+0.158	+0.990	.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,031 associations by consensus.

Protein localization to condensed chromosome by TBC1D31 expression — OESOPHAGUS

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