TBC1D3

Across TCGA patient cohorts, TBC1D3 RNA expression is significantly associated with the protein abundance of many other proteins, with 937 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBC1D3-associated proteins across cancer lineages are MIA3_S1678, C9orf78_S261, and NME3. Each is linked with TBC1D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3-to-partner and partner-to-TBC1D3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D3 versus MIA3_S1678 in LSCC, with a Pearson correlation of -0.22.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3→partner) and Y-score (partner→TBC1D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MIA3_S1678 →	-0.355	-0.153	.006	.005	3	2
LSCC	C9orf78_S261 →	-0.411	-0.135	<.001	<.001	3	2
HNSC	NME3 →	-0.230	-0.080	.001	.009	3	1
LSCC	UBTF_S433 →	-0.362	-0.228	.006	.007	3	1
LSCC	UCKL1_S539 →	-0.439	-0.117	<.001	.004	3	1
LSCC	VANGL1_S338 →	+0.794	+0.207	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 937 associations by consensus.

TBC1D3 vs MIA3_S1678 — LSCC

Explore this scatter interactively →