TBC1D3

Across TCGA patient cohorts, TBC1D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,347 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TBC1D3-associated GO terms across cancer lineages are Pigment biosynthetic process, Endoplasmic reticulum tubular network formation, and Hippocampus development. Each is linked with TBC1D3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D3-to-partner and partner-to-TBC1D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pigment biosynthetic process grouped by TBC1D3-low versus TBC1D3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3→partner) and Y-score (partner→TBC1D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Pigment biosynthetic process →	+0.021	+0.029	.004	.005	3	3
KIRC	Endoplasmic reticulum tubular network formation →	+0.027	+0.032	<.001	<.001	3	3
LIHC	Hippocampus development →	+0.016	+0.017	.002	.001	3	3
COAD	Formation of translation preinitiation complex →	+0.025	+0.020	<.001	<.001	3	3
COAD	N-terminal peptidyl-methionine acetylation →	+0.025	+0.018	.001	<.001	3	2
STAD	Chondrocyte differentiation →	+0.027	+0.039	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,347 associations by consensus.

Pigment biosynthetic process by TBC1D3 expression — STAD

Explore this box plot interactively →