Across TCGA pan-cancer cohorts, TBC1D28 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TBC1D28 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TBC1D28 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TBC1D28 expression acts as an unfavorable survival marker.

COAD and SKCM are the cancer types where TBC1D28 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.111	0.851	<.001	6	view →
SKCM	OS	Median	III,IV	0.179	0.721	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TBC1D28 tumor-vs-normal RNA expression · all TBC1D28 data types